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Benjamin Walter, Ph.D.

  • Assistant Professor, Biomedical Engineering
  • 1080 Carmack Road
    Columbus, OH 43210

About

Dr. Benjamin Walter is a Post-Doctural Researcher in the Spine Research Institute. Within the SRI, Ben’s research focuses on how changes in intervertebral disc biomechanics, which occur with disease, influence the cellular response to physiologic loading. He received his PhD in Biomedical Engineering from The City College of New York and conducted his doctoral research at the Icahn School of Medicine at Mount Sinai in New York City.  Ben received his B.S. (2008) and M.S. (2010) in Biomedical Engineering from Rose-Hulman Institute of Technology and the University of Vermont, respectively. His background is in whole IVD organ culture and cell culture models of intervertebral disc degeneration, with an emphasis on how inflammation contributes to altered disc mechanical behavior and mechanotransduction.

Journal Articles

2015

  • Walter,Benjamin,A; Likhitpanichkul,Morakot; Illien-Junger,Svenja; Roughley,Peter,J; Hecht,Andrew,C; Iatridis,James,C, 2015, "TNF alpha Transport Induced by Dynamic Loading Alters Biomechanics of Intact Intervertebral Discs." PLOS ONE 10, no. 3, e0118358 -

2014

  • Walter,B,A; Illien-Juenger,S; NASSER,P,R; Hecht,A,C; Iatridis,J,C, 2014, "Development and validation of a bioreactor system for dynamic loading and mechanical characterization of whole human intervertebral discs in organ culture." JOURNAL OF BIOMECHANICS 47, no. 9, 2095 - 2101.
  • Likhitpanichkul,M; Dreischarf,M; Illien-Junger,S; Walter,B,A; Nukaga,T; Long,R,G; Sakai,D; Hecht,A,C; Iatridis,J,C, 2014, "FIBRIN-GENIPIN ADHESIVE HYDROGEL FOR ANNULUS FIBROSUS REPAIR: PERFORMANCE EVALUATION WITH LARGE ANIMAL ORGAN CULTURE, IN SITU BIOMECHANICS, AND IN VIVO DEGRADATION TESTS." EUROPEAN CELLS & MATERIALS 28, 25 - 38.
  • Illien-Juenger,Svenja; Lu,Young; Purmessur,Devina; Mayer,Jillian,E; Walter,Benjamin,A; Roughley,Peter,J; Qureshi,Sheeraz,A; Hecht,Andrew,C; Iatridis,James,C, 2014, "Detrimental effects of discectomy on intervertebral disc biology can be decelerated by growth factor treatment during surgery: a large animal organ culture model." SPINE JOURNAL 14, no. 11, 2724 - 2732.
  • Walter,B,A; Illien-Jünger,S; NASSER,P,R; Hecht,A,C; Iatridis,J,C, 2014, "Development and validation of a bioreactor system for dynamic loading and mechanical characterization of whole human intervertebral discs in organ culture.." Journal of biomechanics 47, no. 9, 2095 - 2101.
  • Illien-Jünger,Svenja; Lu,Young; Purmessur,Devina; Mayer,Jillian,E; Walter,Benjamin,A; Roughley,Peter,J; Qureshi,Sheeraz,A; Hecht,Andrew,C; Iatridis,James,C, 2014, "Detrimental effects of discectomy on intervertebral disc biology can be decelerated by growth factor treatment during surgery: a large animal organ culture model.." spine journal 14, no. 11, 2724 - 2732.

2013

  • Iatridis,James,C; Nicoll,Steven,B; Michalek,Arthur,J; Walter,Benjamin,A; Gupta,Michelle,S, 2013, "Role of biomechanics in intervertebral disc degeneration and regenerative therapies: what needs repairing in the disc and what are promising biomaterials for its repair?." SPINE JOURNAL 13, no. 3, 243 - 262.
  • Purmessur,D; Walter,B,A; Roughley,P,J; Laudier,D,M; Hecht,A,C; Iatridis,James, 2013, "A role for TNF alpha in intervertebral disc degeneration: A non-recoverable catabolic shift." BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 433, no. 1, 151 - 156.

2011

  • Walter,B,A; Korecki,C,L; Purmessur,D; Roughley,P,J; Michalek,A,J; Iatridis,J,C, 2011, "Complex loading affects intervertebral disc mechanics and biology." OSTEOARTHRITIS AND CARTILAGE 19, no. 8, 1011 - 1018.

2009

  • Korecki,Casey,L; Walter,Benjamin,A; Godburn,Karolyn,E; Iatridis,James,C, 2009, "ASYMMETRIC LOADING PROMOTES EARLY SIGNS OF INTERVERTEBRAL DISC DEGENERATION IN LARGE ANIMAL ORGAN CULTURE." PROCEEDINGS OF THE ASME SUMMER BIOENGINEERING CONFERENCE - 2009, PT A AND B 2009, 151 - 152.

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